Oura Ring Gen 4 sensor data, not clinical measurementsN=1 case study, not validated for clinical decisionsHEV diagnosed Mar 18; Day 109 post-ruxolitinibMore
Consumer wearable data can support exploratory review only. The HEV diagnosis, temporally confounded with treatment start, remains a material confounder.

Foundation Model Forecasting

Amazon Chronos-2 + ARIMA Statistical Baseline - Oura Ring Biometrics, Post-HSCT
Foundation Model
Watch
unavailable
ModuleNotFoundError: No module named 'torch'
RMSSD MAE
Watch
N/Ams
90% PI coverage: N/A%
HR MAE
Watch
N/Abpm
90% PI coverage: N/A%
Feb 9 Chronos Holdout
Watch
Not run
Chronos retrospective holdout unavailable
Ruxolitinib Start
Info
16. mar 2026
March Ensemble
ARIMA only
0 HIGH confidence anomalies | Feb 9 not detected
NIGHTLY FORECAST

1. Nightly RMSSD and HR - Chronos unavailable

Chronos could not be loaded in this run, so nightly foundation-model forecast charts were skipped. Statistical baseline outputs remain below.

HOURLY HR

2. Continuous HR - Chronos unavailable

Hourly Chronos analysis was skipped because the Chronos pipeline was unavailable.

ENSEMBLE

3. Statistical Baseline - ARIMA

Chronos was unavailable, so the consensus view is reduced to the statistical baseline only.

FEB9 RETRO

4. Feb 9 Retrospective Validation

Retrospective Chronos validation was skipped because the foundation model was unavailable.

Feb 9 Detection Summary
MethodSeriesDetected?Residual
Chronos retrospective not available in this run.

Prospective March ensemble HIGH-confidence anomalies: None detected
Feb 9 in March ensemble consensus: No

RUXOLITINIB

5. Pre vs Post Ruxolitinib Regime Analysis

Pre/post-ruxolitinib Chronos regime analysis was skipped because the foundation model was unavailable.

METRICS

Detailed Metrics

SectionMetricValue
data_range
start2026-01-08
end2026-07-02
n_nights178
ensemble_consensus
errorno overlapping forecasts
statistical_hr
modelARIMA(0, 1, 2)
mae4.270
rmse5.493
coverage_90ci100.000
n_anomalies0
anomaly_dates
statistical_rmssd
modelARIMA(0, 1, 1)
mae1.448
rmse1.843
coverage_90ci92.900
n_anomalies1
anomaly_dates2026-03-09
N=1 retrospective case study. All detection metrics are descriptive, not inferential. The model was trained and evaluated on a single patient's data. Validation requires an external multi-patient cohort.